CO-FORMULATION OF THE RF1V PLAGUE VACCINE WITH DEPOT-FORMULATED CYTOKINES ENHANCES IMMUNOGENICITY AND EFFICACY TO ELICIT PROTECTIVE RESPONSES AGAINST AEROSOL CHALLENGE IN MICE

Co-formulation of the rF1V plague vaccine with depot-formulated cytokines enhances immunogenicity and efficacy to elicit protective responses against aerosol challenge in mice

This study evaluated a depot-formulated cytokine-based adjuvant to improve the efficacy of the recombinant F1V (rF1V) plague vaccine and examined the protective response following aerosol challenge in a murine model.The results of this study showed that co-formulation of the Frypans Alhydrogel-adsorbed rF1V plague fusion vaccine with the depot-form

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